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Beilstein J. Org. Chem. 2019, 15, 937–946, doi:10.3762/bjoc.15.90
Graphical Abstract
Figure 1: Structure of the β-thiols 1a and 1b and of the commercial alkenes 2a and 2b.
Scheme 1: Synthesis of the n-alkyl thioglycosides 3–5, 7 and 8. Detailed reaction conditions are reported in ...
Scheme 2: Synthesis of the lipophilic scaffold 6; DMAP = N,N-dimethylaminopyridine.
Figure 2: Periodic monitoring by 1H NMR (300 MHz, DMF-d7) of the formation of product 8 from a mixture compou...
Figure 3: Micrographs of giant vesicles and lipid aggregates obtained from the gentle hydration (in PBS, pH 7...
Figure 4: A simplified (and not in scale) representation of the ELLA assay, to study the interaction between ...
Figure 5: Inhibition curves for the binding of WGA-HRP to PAA-GlcNAc by D-GlcNAc The symbols (■), () and (○) ...
Figure 6: Main poses obtained from docking experiments. WGA (PDB 2UVO) surface is shown in white for monomer ...